Emerging midfielders Jai Culley and Campbell Chesser are among four inclusions to take on St Kilda, as star Elliot Yeo is forced out of the line-up due to soreness.
Yeo’s absence from the flight east followed confirmation earlier on Thursday that leading goalkicker Jake Waterman (knee) would join co-captain Liam Duggan (concussion) and recruit Tyler Brockman (ankle) on the sidelines.
Speedy forward-mid Jack Petruccelle is back after a three-game absence due to a hamstring strain, with versatile defender Josh Rotham also called in by match committee.
West Coast’s four inclusions have been named on the bench alongside Jamaine Jones for the 1.45pm local (11.45am WA) battle at Marvel Stadium on Saturday.
It will be Culley’s second AFL appearance for the season, coming off an impressive 21-disposal, two-goal effort for the WAFL Eagles in last round’s win over West Perth.