Another brush with injury misfortune has taken the task of West Coast's team selection largely out of the match committee’s hands for Sunday’s clash against unbeaten reigning premier Melbourne at Optus Stadium.

With veteran Shannon Hurn (calf) and wingman Andrew Gaff (quad) ruled out after pulling up sore from main training, only 24 listed players have been deemed fit and available for a considerable challenge against the Demons.

Following stints in the AFL Health and Safety Protocols, midfielder Greg Clark returns for his second game and defender Jackson Nelson is also back after his period of isolation.

They join ruck Bailey Williams (hamstring) and half-back Alex Witherden (Health and Safety) as inclusions to the team that went down to Brisbane at the Gabba by 75 points.

Covid contingency list pair Jake Florenca and Declan Mountford (medi-sub) have gone out of the team, with wingman Patrick Naish omitted.

Naish, tall forward Hugh Dixon, plus CCL duo Tom Blechynden (South Fremantle) and Sam Fisher (Swan Districts) are emergencies.

Star defender Jeremy McGovern will captain the team again in Luke Shuey's absence due to a hamstring niggle. 

A host of other first-choice Eagles are also unavailable, including small forward Willie Rioli, who coach Adam Simpson - recently out of isolation himself - confirmed had sustained a six-week hamstring injury during the last home game against Richmond.