West Coast ruckman Nic Naitanui has been ruled out of Sunday's Western Derby at Domain Stadium, while star Fremantle pair Matthew Pavlich and David Mundy are in doubt.
Naitanui is still in Fiji following the death of his mother, with the funeral to be held on Friday.
"He won't be available this week," Eagles coach Adam Simpson said.
"He's travelling as well as he could be. The funeral arrangements are for Friday. So he'll come back next week.
"Obviously it's family first. It's an emotional time and we'll back away."
Simpson said Jeremy McGovern (hamstring) would join Mark LeCras (suspended) on the sidelines for the top-of-the-table clash.
Dockers Mundy and Pavlich both underwent scans on Monday, with coach Ross Lyon saying they're in doubt for the Derby.
But Lyon was unsure as to the exact nature of their injuries.
"I don't know yet myself," he said on Tuesday.
"They seem to be significant. If you go in for a scan, you've clearly got some doubt about you.
"We'll have to work through the week. Hopefully they can recover.
"Hopefully they can train by the end of the week."
Star Dockers midfielder Nat Fyfe (groin) is a certainty to return unless he suffers a fresh setback at training, while defender Michael Johnson is also in the frame after recovering from a torn hamstring.